# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307634 | Binding | Inhibition of full length GST-tagged human PRKD1 expressed in Baculovirus expression system using ATP as substrate incubated for 1 to 2 hrs by transcreener ADP assay based fluorescence correlation spectroscopic analysis | Homo sapiens | 15 | ALA4304809 | assay format | Scientific Literature | |
2. | ALA4307635 | Binding | Inhibition of NIK (unknown origin) using ATP as substrate by transcreener ADP assay based fluorescence correlation spectroscopic analysis | Homo sapiens | 16 | ALA4304809 | single protein format | Scientific Literature | |
3. | ALA4307636 | Binding | Selectivity ratio of Ki for NIK (unknown origin) to Ki for full length GST-tagged human PRKD1 expressed in Baculovirus expression system | Homo sapiens | 15 | ALA4304809 | assay format | Scientific Literature | |
4. | ALA4307637 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 | 5 | ALA4304809 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4307644 | Binding | Inhibition of full length His-tagged recombinant human AURKB expressed in Baculovirus expression system at 0.1 uM using Fluorescein-PKC as substrate incubated for 1 hr by TR-FRET assay relative to control | Homo sapiens | 2 | ALA4304809 | assay format | Scientific Literature | |
6. | ALA4307645 | Physicochemical | Kinetic solubility of the compound | 3 | ALA4304809 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4307646 | ADME | Metabolic stability in human liver microsomes | Homo sapiens | 3 | ALA4304809 | microsome format | Scientific Literature | |
8. | ALA4307647 | ADME | Metabolic stability in rat liver microsomes | Rattus norvegicus | 3 | ALA4304809 | microsome format | Scientific Literature | |
9. | ALA4307648 | ADME | Metabolic stability in mouse liver microsomes | Mus musculus | 3 | ALA4304809 | microsome format | Scientific Literature |