# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4309849 | Binding | Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assay | Homo sapiens | 34 | ALA4308843 | subcellular format | Scientific Literature | |
2. | ALA4309850 | Binding | Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assay | Homo sapiens | 34 | ALA4308843 | subcellular format | Scientific Literature | |
3. | ALA4309851 | Binding | Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assay | Homo sapiens | 33 | ALA4308843 | subcellular format | Scientific Literature | |
4. | ALA4309853 | Binding | Inhibition of MGLL derived from mouse brain homogenates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assay | Mus musculus | 16 | ALA4308843 | tissue-based format | Scientific Literature | |
5. | ALA4309854 | Functional | In-vivo inhibition of MGLL in ICR mouse brain assessed as target engagement at 5 mg/kg, po measured 4 hrs post dose by gel-based ABPP assay relative to control | Mus musculus | 12 | ALA4308843 | organism-based format | Scientific Literature |