# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4344213 | B | Antagonist activity at human CCR8 expressed in CHOK1 cells assessed as inhibition in CCL1-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by CCL1 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
2. | ALA4344214 | B | Antagonist activity at human Gs/Gi/o-coupled CHRM4 expressed in CHOK1 cells assessed as inhibition in acetylcholine-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by acetylcholine addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
3. | ALA4344215 | B | Antagonist activity at human Gi/o-coupled CNR1 expressed in CHOK1 cells assessed as inhibition in CP55940-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by CP55940 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
4. | ALA4344216 | B | Antagonist activity at human Gi/o-coupled CNR2 expressed in CHOK1 cells assessed as inhibition in CP55940-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by CP55940 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
5. | ALA4344217 | B | Antagonist activity at human Gi/o-coupled CXCR4 expressed in mouse C2C12 cells assessed as inhibition in CXCL12-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by CXCL12 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
6. | ALA4344218 | B | Antagonist activity at human Gi/o-coupled DRD2L expressed in CHOK1 cells assessed as inhibition in dopamine-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by dopamine addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
7. | ALA4344219 | B | Antagonist activity at human Gi/o-coupled FPR1 expressed in CHOK1 cells assessed as inhibition in WKYMVm-NH2-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by WKYMVm-NH2 addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
8. | ALA4344220 | B | Antagonist activity at human GPR119 assessed as inhibition in oleoylethanolamide-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by oleoylethanolamide addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | single protein format | Scientific Literature | |
9. | ALA4344221 | B | Antagonist activity at human Gq-coupled HCRTR2 expressed in CHOK1 cells assessed as inhibition in Orexin A-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by Orexin A addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
10. | ALA4344222 | B | Antagonist activity at human Gq-coupled HRH1 expressed in CHOK1 cells assessed as inhibition in histamine-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by histamine addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
11. | ALA4344223 | B | Antagonist activity at human Gq-coupled NPSR1b expressed in human U2OS cells assessed as inhibition in neuropeptide S-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by neuropeptide S addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
12. | ALA4344224 | B | Antagonist activity at human Gq-coupled PRLHR expressed in CHOK1 cells assessed as inhibition in prolactin releasing peptide (1 to 31)-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by prolactin releasing peptide (1 to 31) addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | cell-based format | Scientific Literature | |
13. | ALA4344225 | B | Antagonist activity at human Gs-coupled PTGIR assessed as inhibition in beraprost-induced beta-arrestin 2 recruitment at 20 uM incubated for 30 mins followed by beraprost- addition and measured after 90 or 180 mins by pathhunter beta-arrestin assay relative to control | Homo sapiens | 9 | ALA4342456 | single protein format | Scientific Literature |