# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4326703 | Binding | Binding affinity to phosphorylated TTBK1 (unknown origin) by SPR analysis | Homo sapiens | 2 | ALA4325845 | single protein format | Scientific Literature | |
2. | ALA4326704 | Binding | Binding affinity to phosphorylated TTBK1 (unknown origin) assessed as association rate constant by SPR analysis | Homo sapiens | 2 | ALA4325845 | single protein format | Scientific Literature | |
3. | ALA5156816 | Binding | Binding affinity to CM5 sensor chip immobilized C-terminal His6/TEV fused-GST-tagged human TTBK1 (14 to 313 residues) expressed in baculovirus infected Sf9 insect cells assessed as dissociation constant measured after 180 secs by surface plasmon resonance analysis | Homo sapiens | 2 | ALA5154682 | cell-based format | Scientific Literature | |
4. | ALA5156818 | Binding | Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATP | Homo sapiens | 50 | ALA5154682 | single protein format | Scientific Literature | |
5. | ALA5156820 | Binding | Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATP | Homo sapiens | 46 | ALA5154682 | single protein format | Scientific Literature | |
6. | ALA5156826 | Functional | Neuroprotective activity against ethacrynic acid-induced neurotoxicity human SH-SY5Y cells assessed as decrease in TDP-43 phosphorylation at Ser410 at 5 uM preincubated for 1 hr followed by EA addition and further incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154682 | cell-based format | Scientific Literature |