# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4480226 | Binding | Inhibition of SETD8 (unknown origin) using biotin-labeled histone H4 (1 to 24 residues) as substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
2. | ALA4480230 | Binding | Inhibition of N-terminal His6-tagged human SETD2 (1347 to 1711 residues) expressed in Escherichia coli Rosseta-2(DE3) cells assessed as residual activity at 50 uM using biotinylated-histone H3 (20 to 50 residues) as substrate in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | cell-based format | Scientific Literature | |
3. | ALA4480231 | Binding | Inhibition of PRDM9 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
4. | ALA4480232 | Binding | Inhibition of EZH2 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
5. | ALA4480233 | Binding | Inhibition of SUV39H1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
6. | ALA4480234 | Binding | Inhibition of SUV39H2 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
7. | ALA4480235 | Binding | Inhibition of SETDB1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
8. | ALA4480236 | Binding | Inhibition of MLL1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
9. | ALA4480237 | Binding | Inhibition of MLL3 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
10. | ALA4480238 | Binding | Inhibition of NSD1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
11. | ALA4480239 | Binding | Inhibition of NSD2 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
12. | ALA4480240 | Binding | Inhibition of NSD3 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
13. | ALA4480241 | Binding | Inhibition of DOT1L (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
14. | ALA4480242 | Binding | Inhibition of ASH1L (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
15. | ALA4480243 | Binding | Inhibition of PRMT1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
16. | ALA4480244 | Binding | Inhibition of PRMT5 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
17. | ALA4480245 | Binding | Inhibition of PRMT6 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
18. | ALA4480246 | Binding | Inhibition of PRMT7 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
19. | ALA4480247 | Binding | Inhibition of PRMT8 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature | |
20. | ALA4480248 | Binding | Inhibition of METTL21A (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | ALA4477270 | single protein format | Scientific Literature |