# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4393627 | Functional | Immunosuppressant activity in human T lymphocytes assessed as inhibition of anti-human CD3 and anti-human CD28 monoclonal antibody-induced T lymphocyte proliferation incubated for 72 hrs by FACS analysis | Homo sapiens | 11 | ALA4392884 | cell-based format | Scientific Literature | |
2. | ALA4393628 | Toxicity | Toxicity in anti-human CD3 and anti-human CD28 monoclonal antibody-stimulated human T lymphocytes assessed as induction of apoptosis at 3 times antiproliferative IC50 incubated for 48 hrs by annexin V-FITC and propidium iodide staining based FACS analysis | Homo sapiens | 1 | ALA4392884 | cell-based format | Scientific Literature | |
3. | ALA5131143 | Binding | Inhibition of PI3K/AKT signalling pathway in human MM121224 cells stably expressing H2B-mTurquoise, ERK-KTR-mScarlet and FoxO3a-KTR-mNeonGreen fluorophore assessed as AKT activity by high-content screening microscopic analysis | Homo sapiens | 35 | ALA5126665 | cell-based format | Scientific Literature | |
4. | ALA5131144 | Binding | Inhibition of MAPK/ERK signalling pathway in human MM121224 cells stably expressing H2B-mTurquoise, ERK-KTR-mScarlet and FoxO3a-KTR-mNeonGreen fluorophore assessed as effect on EKR-KTR activity by high-content screening microscopic analysis | Homo sapiens | 35 | ALA5126665 | cell-based format | Scientific Literature |