#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4482492	Binding	Displacement of [125I]-C5a from C5a2 receptor (unknown origin) expressed in Flp-In CHO cell membranes at 100 uM incubated for 1 hr by microbeta scintillation counting assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
2.	ALA4482493	Binding	Displacement of [125I]-C5a from C5a2 receptor (unknown origin) expressed in Flp-In CHO cell membranes incubated for 1 hr by microbeta scintillation counting assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
3.	ALA4482494	Binding	Displacement of [125I]-C5a from C5a1 receptor (unknown origin) expressed in Flp-In CHO cell membranes incubated for 1 hr by microbeta scintillation counting assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
4.	ALA4482496	Binding	Partial agonist activity at C5a2 receptor (unknown origin) expressed in HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 1 hr by BRET assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
5.	ALA4482497	Binding	Partial agonist activity at C5a2 receptor (unknown origin) expressed in HEK293 cells assessed as induction of beta-arrestin-2 recruitment incubated for 1 hr by BRET assay relative to C5a	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
6.	ALA4482498	Binding	Agonist activity at C5a1 receptor (unknown origin) expressed in HEK293 cells assessed as induction of beta-arrestin-2 recruitment at 100 uM incubated for 1 hr by BRET assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
7.	ALA4482499	Binding	Partial agonist activity at human C5a2 receptor assessed as induction of beta-arrestin-2 recruitment by DiscoverX Path Hunter kit based assay	Homo sapiens	2	ALA4482309	single protein format	Patent Bioactivity Data
8.	ALA4482500	Binding	Partial agonist activity at human C5a1 receptor assessed as induction of beta-arrestin-2 recruitment by DiscoverX Path Hunter kit based assay	Homo sapiens	2	ALA4482309	single protein format	Patent Bioactivity Data
9.	ALA4482501	Binding	Induction of C5a1-C5a2 heteromer formation (unknown origin) expressed in HEK293 cells at 100 uM by BRET assay	Homo sapiens	2	ALA4482309	cell-based format	Patent Bioactivity Data
10.	ALA4482502	Binding	Agonist activity at C5a2 receptor in HMDM assessed as inhibition of LPS-induced IL-6 release at 10 to 100 uM by ELISA	Homo sapiens	1	ALA4482309	single protein format	Patent Bioactivity Data
11.	ALA4482503	Binding	Agonist activity at C5a2 receptor in HMDM assessed as inhibition of LPS-induced TNFalpha release at 0.1 to 100 uM by ELISA	Homo sapiens	2	ALA4482309	single protein format	Patent Bioactivity Data
12.	ALA4482504	Binding	Agonist activity at C5a2 receptor in LPS-induced IHMDM assessed as effect on L10 release at 0.1 to 100 uM by ELISA	Homo sapiens	2	ALA4482309	single protein format	Patent Bioactivity Data
13.	ALA4482506	Binding	Agonist activity at C5a2 receptor in HMDM assessed as inhibition of LPS-induced TNFalpha release at 100 uM in presence of C5a1 antagonist PMX53 by ELISA	Homo sapiens	2	ALA4482309	single protein format	Patent Bioactivity Data
14.	ALA4482507	Binding	Induction of ERK1/2 phosphorylation in HMDM at 100 uM incubated for 30 mins	Homo sapiens	2	ALA4482309	protein format	Patent Bioactivity Data
15.	ALA4482508	Binding	Agonist activity at C5a2 receptor in HMDM assessed as inhibition of C5a-induced induction of ERK1/2 phosphorylation in HMDM at 100 uM pre-incubated for 30 mins before C5a addition and measured after 10 mins	Homo sapiens	2	ALA4482309	assay format	Patent Bioactivity Data
16.	ALA4482509	Functional	Inhibition of C5a-induced neutrophil mobilization in iv dosed wild type mouse	Mus musculus	1	ALA4482309	organism-based format	Patent Bioactivity Data
17.	ALA4482510	Functional	Inhibition of C5a-induced neutrophil mobilization in iv dosed C5aR2 (-/-) mouse	Mus musculus	1	ALA4482309	organism-based format	Patent Bioactivity Data