# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4482228 | Binding | Inhibition of Wistar rat brain MAOA using kynuramine as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by fluorescence assay | Rattus norvegicus | 3 | ALA4480464 | assay format | Scientific Literature | |
2. | ALA4482229 | Binding | Inhibition of Wistar rat brain MAOB using kynuramine as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins by fluorescence assay | Rattus norvegicus | 3 | ALA4480464 | assay format | Scientific Literature | |
3. | ALA4482230 | Binding | Selectivity index, ratio of IC50 for Wistar rat brain MAOB to Wistar rat brain MAOA | Rattus norvegicus | 2 | ALA4480464 | assay format | Scientific Literature | |
4. | ALA4482232 | ADME | Cytotoxicity against LPS-induced mouse RAW264.7 cells assessed as cell killing at 123 to 164 uM measured after 24 hrs by resazurin dye based fluorescence assay | Mus musculus | 1 | ALA4480464 | cell-based format | Scientific Literature | |
5. | ALA4482233 | ADME | Cytotoxicity against LPS-induced mouse RAW264.7 cells assessed as cell viability at 82 uM measured after 24 hrs by resazurin dye based fluorescence assay | Mus musculus | 1 | ALA4480464 | cell-based format | Scientific Literature | |
6. | ALA4482235 | ADME | Cytotoxicity against LPS-induced mouse RAW264.7 cells assessed as effect on cell viability at 41 uM measured after 24 hrs by resazurin dye based fluorescence assay | Mus musculus | 1 | ALA4480464 | cell-based format | Scientific Literature | |
7. | ALA4482237 | Functional | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production at 41 uM after 24 hrs by Griess assay | Mus musculus | 1 | ALA4480464 | cell-based format | Scientific Literature | |
8. | ALA4482238 | Functional | Cytotoxicity against human MCF7 cells measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4480464 | cell-based format | Scientific Literature | |
9. | ALA4482239 | Functional | Cytotoxicity against human SiHa cells measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4480464 | cell-based format | Scientific Literature | |
10. | ALA4482240 | Functional | Cytotoxicity against human HF6 cells measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4480464 | cell-based format | Scientific Literature | |
11. | ALA4482241 | Functional | Cytotoxicity against human PC3 cells measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4480464 | cell-based format | Scientific Literature | |
12. | ALA4482242 | ADME | Cytotoxicity against human HSF30 cells measured after 72 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA4480464 | cell-based format | Scientific Literature | |
13. | ALA4482243 | Toxicity | Selectivity index, ratio of IC50 for human HSF30 cells to IC50 for human MCF7 cells | Homo sapiens | 4 | ALA4480464 | assay format | Scientific Literature | |
14. | ALA4482244 | Toxicity | Selectivity index, ratio of IC50 for human HSF30 cells to IC50 for human SiHa cells | Homo sapiens | 4 | ALA4480464 | assay format | Scientific Literature | |
15. | ALA4482245 | Unassigned | Selectivity index, ratio of IC50 for human HSF30 cells to IC50 for human HF6 cells | Homo sapiens | 4 | ALA4480464 | assay format | Scientific Literature | |
16. | ALA4482246 | Toxicity | Selectivity index, ratio of IC50 for human HSF30 cells to IC50 for human PC3 cells | Homo sapiens | 4 | ALA4480464 | assay format | Scientific Literature |