| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4305041 | B | Selectivity ratio of IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells to IC50 for human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 2 | ALA4304742 | cell-based format | Scientific Literature | |
| 2. | ALA4305042 | B | Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay | Homo sapiens | 62 | ALA4304742 | cell-based format | Scientific Literature | |
| 3. | ALA4305044 | B | Inhibition of human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 insect cells using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay | Homo sapiens | 62 | ALA4304742 | cell-based format | Scientific Literature | |
| 4. | ALA4305046 | B | Inhibition of human full-length N-terminal GST-tagged PARP3 expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | cell-based format | Scientific Literature | |
| 5. | ALA4305047 | B | Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | cell-based format | Scientific Literature | |
| 6. | ALA4305048 | B | Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | cell-based format | Scientific Literature | |
| 7. | ALA4305049 | B | Inhibition of PARP8 (unknown origin) at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | single protein format | Scientific Literature | |
| 8. | ALA4305050 | B | Inhibition of human N-terminal FLAG-tagged/C-terminal Strep-tagged PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | cell-based format | Scientific Literature | |
| 9. | ALA4305051 | B | Inhibition of human N-terminal His/GST-tagged PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 insect cells at 500 nM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 5 | ALA4304742 | cell-based format | Scientific Literature | |
| 10. | ALA4305052 | B | Inhibition of human full-length N-terminal GST-tagged PARP3 expressed in baculovirus infected Sf9 insect cells at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 11. | ALA4305053 | B | Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 12. | ALA4305054 | B | Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 13. | ALA4305055 | B | Inhibition of PARP8 (unknown origin) at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | single protein format | Scientific Literature | |
| 14. | ALA4305056 | B | Inhibition of human N-terminal FLAG-tagged/C-terminal Strep-tagged PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 15. | ALA4305057 | B | Inhibition of human N-terminal His/GST-tagged PARP14 (1470 to 1801 residues) expressed in baculovirus infected Sf9 insect cells at 1 uM using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay relative to control | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 16. | ALA4305058 | B | Selectivity ratio of IC50 for human full-length N-terminal GST-tagged PARP3 expressed in baculovirus infected Sf9 insect cells to IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 17. | ALA4305059 | B | Selectivity ratio of IC50 for human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected Sf9 insect cells to IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 18. | ALA4305060 | B | Selectivity ratio of IC50 for human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected Sf9 insect cells to IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 19. | ALA4305061 | B | Selectivity ratio of IC50 for PARP8 (unknown origin) to IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature | |
| 20. | ALA4305062 | B | Selectivity ratio of IC50 for human N-terminal FLAG-tagged/C-terminal Strep-tagged PARP10 (805 to 1025 residues) expressed in baculovirus infected Sf9 insect cells to IC50 for human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | ALA4304742 | cell-based format | Scientific Literature |
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