| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4398995 | A | Cytotoxicity against mouse RAW264.7 cells assessed as effect on cell viability at 6.25 to 100 uM cotreated with PAM3CSK4 measured after 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4398996 | B | Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assay | Mus musculus | 34 | cell-based format | Scientific Literature | ||
| 3. | ALA4398997 | B | Inhibition of TLR2 in human HEK-Blue hTLR2 cells assessed as suppression of PAM3CSK4-induced SEAP signaling at 25 uM after 24 hrs by quanti-blue assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4398998 | B | Inhibition of TLR2 in human HEK-Blue hTLR2 cells assessed as suppression of PAM3CSK4-induced SEAP signaling after 24 hrs by quanti-blue assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4398999 | B | Inhibition of Poly:IC-induced TLR3 activation in human HEK-Blue hTLR3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4399001 | B | Inhibition of PAM3CSK4-induced TLR1/2 activation in human HEK-Blue hTLR2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4399002 | B | Inhibition of PAM2CSK4-induced TLR2/6 activation in human HEK-Blue hTLR2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4399003 | B | Inhibition of LPS-induced TLR4 activation in human HEK-Blue hTLR4 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4399004 | F | Inhibition of PAM3CSK4-induced TLR2 expression in human HEK-Blue Htlr2 cells at 12.5 uM by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4399005 | B | Inhibition of TLR2 in human PBMC cells assessed as PAM3CSK4-induced TLR1/2 heterodimerization formation by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4399006 | B | Inhibition of TLR2 in human PBMC cells assessed as PAM2CSK4-induced TLR2/6 heterodimerization formation by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4399007 | B | Inhibition of TLR2 in human PBMC cells assessed as PAM3CSK4-induced TLR2/Myd88 heterodimerization formation by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4399008 | B | Inhibition of TLR2 in mouse RAW264.7 cells assessed as decrease in PAM3CSK4 induced TNF-alpha expression at 25 uM measured after 24 hrs by ELISA relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4399009 | B | Inhibition of TLR2 in human THP1 assessed as decrease in PAM3CSK4 induced TNF-alpha expression measured after 24 hrs by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4399010 | B | Inhibition of TLR2 in human PBMC cells assessed as decrease in PAM3CSK4 induced TNF-alpha expression at 12.5 uM measured after 24 hrs by ELISA relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4399011 | B | Inhibition of TLR2 in mouse RAW264.7 cells assessed as decrease in PAM3CSK4 induced TNF-alpha expression measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4399012 | B | Inhibition of TLR2 in human PBMC cells assessed as PAM2CSK4-induced TLR2/Myd88 heterodimerization formation by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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