| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4480313 | B | Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by TR-FRET assay | Homo sapiens | 39 | single protein format | Scientific Literature | ||
| 2. | ALA4480314 | P | Solubility of compound in water by lyophilized solubility assay | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4480315 | B | Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 4. | ALA4480316 | A | Cytotoxicity against HEK293T cells after 24 hrs | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 5. | ALA4480317 | A | Clearance in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 6. | ALA4480318 | A | Clearance in mouse liver microsomes | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 7. | ALA4480319 | B | Covalent binding to ATG4B (unknown origin) assessed as interaction at Cys-74 residue by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4480320 | B | Inhibition of recombinant human cathepsin D (400 residues) expressed in CHO cells using 5-FAM/QXL 520 FRET peptide as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4480321 | B | Inhibition of cathepsin G (unknown origin) using Suc-AAPF-pNA as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 10. | ALA4480322 | B | Inhibition of tryptase beta2 (unknown origin) using Z-GPR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA4480323 | B | Inhibition of 20S proteasome (unknown origin) using suc-LLVY-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 12. | ALA4480324 | B | Inhibition of neutrophil elastase (unknown origin) using MeOSu-AAPV-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4480325 | B | Inhibition of caspase2 (unknown origin) using ICH-1 as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA4480326 | B | Inhibition of caspase3 (unknown origin) using Ac-DMQD-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4480327 | B | Inhibition of caspase7 (unknown origin) using Ac-LEHD-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA4480328 | B | Inhibition of caspase8 (unknown origin) using Ac-LEHD-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA4480329 | B | Inhibition of caspase9 (unknown origin) using Ac-LEHD-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4480330 | B | Inhibition of recombinant human cathepsin B (332 residues) expressed in CHO cells using Z-FR-AMC as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4480332 | B | Inhibition of calpain (unknown origin) using calpain substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | protein format | Scientific Literature | ||
| 20. | ALA4480333 | B | Inhibition of ACE (unknown origin) using Mca-RPPGFSAFK (Dnp) as substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature |
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