# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4343181 | Functional | Antiproliferative activity against human SUM159 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 29 | ALA4342417 | cell-based format | Scientific Literature | |
2. | ALA4343182 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 29 | ALA4342417 | cell-based format | Scientific Literature | |
3. | ALA4343183 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 29 | ALA4342417 | cell-based format | Scientific Literature | |
4. | ALA4343184 | Functional | Antiproliferative activity against human SKBR3 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 29 | ALA4342417 | cell-based format | Scientific Literature | |
5. | ALA4343185 | Functional | Potency index, ratio of IC50 of TFP to IC50 of compound for antiproliferative activity against human SUM159 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 8 | ALA4342417 | cell-based format | Scientific Literature | |
6. | ALA4343187 | Functional | Potency index, ratio of IC50 of TFP to IC50 of compound for antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 5 | ALA4342417 | cell-based format | Scientific Literature | |
7. | ALA4343189 | Functional | Antiproliferative activity against human KG1a cells assessed as reduction in cell viability incubated for 2 days by MTT assay | Homo sapiens | 8 | ALA4342417 | cell-based format | Scientific Literature | |
8. | ALA4343190 | ADME | Toxicity in zebra fish assessed as survival rate at 250 uM observed for 24 hrs | Danio rerio | 6 | ALA4342417 | assay format | Scientific Literature | |
9. | ALA4343191 | Functional | Inhibition of colony formation in human MCF7 cells at 0.18 uM incubated for 14 days with replacement of medium for every 3 or 4 days by crystal violet staining based visual analysis relative to control | Homo sapiens | 1 | ALA4342417 | cell-based format | Scientific Literature | |
10. | ALA4343192 | Functional | Inhibition of colony formation in human MCF7 cells at 0.37 uM incubated for 14 days with replacement of medium for every 3 or 4 days by crystal violet staining based visual analysis relative to control | Homo sapiens | 1 | ALA4342417 | cell-based format | Scientific Literature | |
11. | ALA4343193 | Functional | Inhibition of colony formation in human MCF7 cells at 0.74 uM incubated for 14 days with replacement of medium for every 3 or 4 days by crystal violet staining based visual analysis relative to control | Homo sapiens | 1 | ALA4342417 | cell-based format | Scientific Literature | |
12. | ALA4343196 | Functional | Inhibition of colony formation in human MCF7 cells incubated for 14 days with replacement of medium for every 3 or 4 days by crystal violet staining based visual analysis | Homo sapiens | 2 | ALA4342417 | cell-based format | Scientific Literature | |
13. | ALA4343197 | Functional | Inhibition of mammosphere formation in human SUM159 cells incubated for 10 days by microscopic analysis | Homo sapiens | 2 | ALA4342417 | cell-based format | Scientific Literature | |
14. | ALA4343198 | Functional | Inhibition of mammosphere formation in human SUM159 cells assessed as reduction in number of mammosphere at 0.5 uM incubated for 10 days by microscopic analysis | Homo sapiens | 2 | ALA4342417 | cell-based format | Scientific Literature | |
15. | ALA4343199 | Functional | Inhibition of mammosphere formation in human SUM159 cells assessed as reduction in number of mammosphere at 1 uM incubated for 10 days by microscopic analysis | Homo sapiens | 2 | ALA4342417 | cell-based format | Scientific Literature | |
16. | ALA4343200 | Functional | Inhibition of mammosphere formation in human SUM159 cells assessed as reduction in number of mammosphere at 2 uM incubated for 10 days by microscopic analysis | Homo sapiens | 3 | ALA4342417 | cell-based format | Scientific Literature | |
17. | ALA4343201 | Functional | Inhibition of cell migration of human MDA-MB-231 cells incubated for 48 hrs by scratch wound healing assay | Homo sapiens | 1 | ALA4342417 | cell-based format | Scientific Literature | |
18. | ALA4343204 | Binding | Inhibition of LPS-stimulated NF-kappaB-p65 in human MDA-MB-231 cells incubated for 24 hrs by dual luciferase reporter gene assay | Homo sapiens | 1 | ALA4342417 | cell-based format | Scientific Literature | |
19. | ALA4343206 | Functional | Downregulation of NF-kappaB-p65 expression in human MDA-MB-231 cells incubated for 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA4342417 | cell-based format | Scientific Literature |