| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4367522 | B | Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated cell proliferation by measuring increase in CD3+ cells preincubated for 3 days followed by 11 days incubation post compound washout and subsequent IL2 stimulation for every 3 days measured after 14 days by flow cytometry | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4367525 | B | Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated cell proliferation by measuring increase in CD3+ cells up to 100 uM preincubated for 3 days followed by 11 days incubation post compound washout and subsequent IL2 stimulation for every 3 days measured after 14 days by flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4367529 | B | Activation of BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of IL2-stimulated IFNgamma production measured after 48 hrs by ELISA | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 4. | ALA4367532 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 full interaction domain (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins in presence of calcium by fluorescence polarization assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA4367534 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 B30.2 domain (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 11 | assay format | Scientific Literature | ||
| 6. | ALA4367538 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 W421A mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA4367539 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 M424A mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA4367540 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 R442A mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA4367541 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 R448A mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4367542 | B | Displacement of GDP-BODIPY from C-terminal 6His-tagged BTN3A1 R499A mutant (unknown origin) expressed in Escherichia coli BL21 (DE) measured after 60 mins by fluorescence polarization assay | Homo sapiens | 3 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!