# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346948 | ADME | Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
2. | ALA4346949 | Unassigned | Selectivity index, ratio of IC50 for human WI38 cells to GI50 for human NCI60 cells | Homo sapiens | 17 | ALA4346657 | assay format | Scientific Literature | |
3. | ALA4347002 | Functional | Antiproliferative activity against human K562 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay | Homo sapiens | 16 | ALA4346657 | cell-based format | Scientific Literature | |
4. | ALA4347009 | ADME | Haemolytic activity in human erythrocytes assessed as induction of hemolysis at 10 mM after 30 mins relative to H202 | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
5. | ALA4347010 | ADME | Haemolytic activity in human erythrocytes assessed as induction of hemolysis at 5 mM after 30 mins relative to H202 | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
6. | ALA4347011 | ADME | Haemolytic activity in human erythrocytes assessed as induction of hemolysis at 2.5 mM after 30 mins relative to H202 | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
7. | ALA4347012 | ADME | Haemolytic activity in human erythrocytes assessed as induction of hemolysis at 1.25 mM after 30 mins relative to H202 | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
8. | ALA4347013 | ADME | Haemolytic activity in human erythrocytes assessed as induction of hemolysis at 0.625 mM after 30 mins relative to H202 | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
9. | ALA4347014 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity incubated in dark for 30 mins by spectrophotometric method relative to control | 17 | ALA4346657 | assay format | Scientific Literature | ||
10. | ALA4347015 | Functional | Antioxidant activity assessed as DPPH radical scavenging activity incubated in dark for 30 mins by spectrophotometric method relative to ascorbic acid | 17 | ALA4346657 | assay format | Scientific Literature | ||
11. | ALA4347016 | Functional | Antioxidant activity assessed as ABTS radical scavenging activity by spectrophotometric analysis relative to control | 17 | ALA4346657 | assay format | Scientific Literature | ||
12. | ALA4347017 | Functional | Antioxidant activity assessed as ABTS radical scavenging activity by spectrophotometric method relative to ascorbic acid | 17 | ALA4346657 | assay format | Scientific Literature | ||
13. | ALA4347018 | Functional | Antioxidant activity assessed as hydroxyl radical scavenging activity after 1 hr by salicylic acid-based Fenton reaction assay | 16 | ALA4346657 | assay format | Scientific Literature | ||
14. | ALA4347019 | Unassigned | Pro-oxidant activity assessed as increase in bleomycin-Fe2+ induced calf thymus DNA damage at 2 mM after 1 hr by thiobarbituric acid based absorbance analysis | 16 | ALA4346657 | assay format | Scientific Literature | ||
15. | ALA4347020 | Functional | Induction of apoptosis in human HCT116 cells assessed as increase in caspase 3 mRNA expression at 100 nM after 6 hrs hrs by SYBR green dye-based qRT-PCR analysis relative to control | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
16. | ALA4347021 | Functional | Induction of apoptosis in human HCT116 cells assessed as increase in caspase 9 mRNA expression at 100 nM after 6 hrs hrs by SYBR green dye-based qRT-PCR analysis relative to control | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
17. | ALA4347022 | Functional | Induction of apoptosis in human HCT116 cells assessed as increase in p53 mRNA expression at 100 nM after 6 hrs hrs by SYBR green dye-based qRT-PCR analysis relative to control | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature | |
18. | ALA4347023 | Functional | Increase in CDK1 mRNA expression in human HCT116 cells at 100 nM after 6 hrs hrs by SYBR green dye-based qRT-PCR analysis relative to control | Homo sapiens | 17 | ALA4346657 | cell-based format | Scientific Literature |