# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417149 | Binding | Induction of cell membrane disruption in human A549 cells assessed as LDH release at 3.25 uM incubated for 30 mins by fluorescence based assay relative to control | Homo sapiens | 9 | ALA4414655 | cell-based format | Scientific Literature | |
2. | ALA4417155 | ADME | Cytotoxicity in human HEK293T cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Homo sapiens | 9 | ALA4414655 | cell-based format | Scientific Literature | |
3. | ALA4417161 | Functional | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Homo sapiens | 9 | ALA4414655 | cell-based format | Scientific Literature | |
4. | ALA4417162 | Functional | Potency index, ratio of IC50 for lycosin-I to IC50 for test compound for cytotoxicity in human A549 cells assessed as reduction in cell viability at 0.78 to 50 uM incubated for 24 hrs by CCK8 assay | Homo sapiens | 8 | ALA4414655 | cell-based format | Scientific Literature | |
5. | ALA4417163 | Functional | Cytotoxicity in human A549 cells assessed as reduction in cell viability by trypan blue staining method | Homo sapiens | 8 | ALA4414655 | cell-based format | Scientific Literature | |
6. | ALA4417172 | Binding | Induction of cell membrane disruption in human erythrocytes cells assessed as induction of hemolysis at 0.098 to 50 uM incubated for 1 hr by fluorescence based assay relative to control | Homo sapiens | 8 | ALA4414655 | cell membrane format | Scientific Literature | |
7. | ALA4417185 | Functional | Cytotoxicity in mouse B16/F10 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Mus musculus | 8 | ALA4414655 | cell-based format | Scientific Literature |