| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4342059 | B | Inhibition of GABA aminotransferase in mouse brain homogenates using GABA and alpha-ketoglutarate as substrates preincubated for 30 mins followed by beta-NADP addition and measured for 20 mins by spectrophotometric method | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 2. | ALA4342060 | T | Neurotoxicity in ip dosed albino mouse assessed as motor impairment measured at 4 hrs by rotarod test | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 3. | ALA4342061 | T | Neurotoxicity in ip dosed albino mouse assessed as motor impairment measured at 0.5 hrs by rotarod test | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 4. | ALA4342062 | F | Anticonvulsant activity in ip dosed albino mouse model of maximal electroshock-induced seizures assessed as prevention of tonic hind limb extension pretreated for 0.5 hrs followed by 50 mA current-induction for 0.25 secs | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 5. | ALA4342063 | F | Anticonvulsant activity in ip dosed albino mouse model of maximal electroshock-induced seizures assessed as prevention of tonic hind limb extension pretreated for 4 hrs followed by 50 mA current-induction for 0.25 secs | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 6. | ALA4342064 | F | Anticonvulsant activity in ip dosed albino mouse model of subcutaneous pentylenetetrazole-induced seizure assessed as failure to observe even a single episode of clonic spasms for at least 5 secs pretreated for 4 hrs followed by pentylenetetrazole induction | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 7. | ALA4342065 | F | Anticonvulsant activity in ip dosed albino mouse model of subcutaneous pentylenetetrazole-induced seizure assessed as failure to observe even a single episode of clonic spasms for at least 5 secs pretreated for 0.5 hrs followed by pentylenetetrazole induction | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 8. | ALA4342066 | F | Anticonvulsant activity in po dosed albino mouse brain assessed as increase in brain GABA level administered for 7 days by TLC analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4342067 | T | Hepatotoxicity in albino mouse assessed as decrease in serum SGOT level at 30 mg/kg, po administered daily for one month measured post-last dose | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA4342068 | T | Hepatotoxicity in albino mouse assessed as decrease in serum SGPT level at 30 mg/kg, po administered daily for one month measured post-last dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4342069 | T | Hepatotoxicity in albino mouse assessed as decrease in serum alkaline phosphatase level at 30 mg/kg, po administered daily for one month measured post-last dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4342072 | T | Hepatotoxicity in albino mouse assessed as appearance of normal hepatocyte with clearing of cytoplasm at 30 mg/kg, po administered daily for one month measured post-last dose by histopathological analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!