# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4411915 | Binding | Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting analysis | Homo sapiens | 40 | ALA4411271 | single protein format | Scientific Literature | |
2. | ALA4411916 | Binding | Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hrs by luciferase reporter gene assay | Homo sapiens | 41 | ALA4411271 | cell-based format | Scientific Literature | |
3. | ALA4411917 | Binding | Induction of full length androgen receptor degradation in human LNCaP cells at 1 uM after 24 hrs in presence of R1881 by Western blot analysis relative to control | Homo sapiens | 41 | ALA4411271 | cell-based format | Scientific Literature | |
4. | ALA4411918 | Binding | Induction of androgen receptor splice variant mutant degradation in human 22RV1 cells at 10 uM after 24 hrs in presence of R1881 by Western blot analysis relative to control | Homo sapiens | 41 | ALA4411271 | cell-based format | Scientific Literature | |
5. | ALA4411919 | Functional | Antiproliferative activity against human MR49F cells after 3 days followed by compound wash and measured after 6 days by SRB assay | Homo sapiens | 35 | ALA4411271 | cell-based format | Scientific Literature |