# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4339970 | Functional | Antagonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of SKF38393-induced cAMP accumulation measured after 30 mins | Homo sapiens | 19 | ALA4339211 | cell-based format | Scientific Literature | |
2. | ALA4339971 | Functional | Antagonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of dopamine-induced calcium flux preincubated for 60 mins at 37 degC followed by 15 mins incubation under room temperature and subsequent dopamine addition measured after 20 secs for 100 secs by calcium-4 dye based FLIPR assay | Homo sapiens | 19 | ALA4339211 | cell-based format | Scientific Literature | |
3. | ALA4339972 | Functional | Agonist activity at D1 receptor (unknown origin) expressed in CHOK1 cells assessed as increase in cAMP accumulation at 10 uM measured after 30 mins | Homo sapiens | 18 | ALA4339211 | cell-based format | Scientific Literature | |
4. | ALA4339973 | Functional | Agonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as increase in calcium flux at 10 uM incubated for 60 mins at 37 degC followed by 15 mins incubation under room temperature measured after 20 secs for 100 secs by calcium-4 dye based FLIPR assay relative to control | Homo sapiens | 18 | ALA4339211 | cell-based format | Scientific Literature |