# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307467 | B | Inhibition of BACE1 (unknown origin) | Homo sapiens | 10 | single protein format | Scientific Literature | ||
2. | ALA4307468 | B | Inhibition of BACE1 in human SKNBE2 cells expressing wild type amyloid precursor protein (APP695) assessed as amyloid beta42 level incubated for 18 hrs by sandwich ELISA | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA4307469 | B | Inhibition of BACE2 (unknown origin) | Homo sapiens | 8 | single protein format | Scientific Literature | ||
4. | ALA4307470 | B | Inhibition of human ERG | Homo sapiens | 8 | single protein format | Scientific Literature | ||
5. | ALA4307471 | A | Ratio of apparent permeability across apical to basolateral side in presence of P-gp inhibitor elacridar over apical to basolateral side in absence of P-gp inhibitor elacridar in mouse LLC cells transfected with human MDR1 at 5 uM by LC/MS-MS analysis | Mus musculus | 8 | cell-based format | Scientific Literature | ||
6. | ALA4307472 | P | Dissociation constant, pKa of compound | 8 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA5041725 | B | Inhibition of BACE1 (1 to 454 residues) (unknown origin) using APP harboring Swedish Lys/Met mutant-derived peptide as substrate by FRET assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
8. | ALA5041726 | A | Apparent permeability across apical to basolateral side in dog MDCK-MDR1 cells at 5 uM incubated for 120 mins in the presence of P-gp inhibitor elacridar | Canis lupus familiaris | 11 | cell-based format | Scientific Literature | ||
9. | ALA5041727 | A | Ratio of apparent permeability across apical to basolateral side in the presence of P-gp inhibitor elacridar to the absence of P-gp inhibitor elacridar in dog MDCK-MDR1 cells at 5 uM incubated for 120 mins | Canis lupus familiaris | 5 | cell-based format | Scientific Literature | ||
10. | ALA5041728 | T | Inhibition of hERG expressed in HEK293 cells at -80 mV holding potential by automated patch-clamp method | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
11. | ALA5041729 | P | Dissociation constant, pKa of the compound by fast UV-spectrometric titration analysis | 5 | small-molecule physicochemical format | Scientific Literature |