| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4334555 | B | Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 2. | ALA4334556 | B | Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Z-Lys(Ac)-AMC as substrate incubated for 90 mins followed by trypsin addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 3. | ALA4334557 | B | Selectivity index, ratio of IC50 for recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells to IC50 for recombinant full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA4334558 | F | Antiproliferative activity against human CHP134 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA4334559 | F | Antiproliferative activity against human IMR32 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 6. | ALA4334560 | F | Antiproliferative activity against human SK-N-AS cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 7. | ALA4334561 | F | Antiproliferative activity against human NB-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA4334562 | F | Antiproliferative activity against human G55T2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay | Homo sapiens | 12 | cell-based format | Scientific Literature |
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