| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4415101 | B | Binding affinity to CD47 in biotinylated human MEC1 cell membranes by biolayer interferometry | Homo sapiens | 13 | ALA4414552 | cell-based format | Scientific Literature | |
| 2. | ALA4415103 | P | Aggregation property of the compound in water | 2 | ALA4414552 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4415104 | A | Aggregation property of the compound in human serum | Homo sapiens | 2 | ALA4414552 | cell-free format | Scientific Literature | |
| 4. | ALA4415105 | F | Cytotoxicity against human MEC1 cells assessed as induction of cell death after 2 hrs by annexin V/propidium iodide staining based flow cytometric analysis | Homo sapiens | 3 | ALA4414552 | cell-based format | Scientific Literature | |
| 5. | ALA4415107 | B | Agonist activity at CD47 in human MEC1 cells assessed as activation of PLCgamma1-induced calcium-mediated caspase-independent cell death at 20 uM after 2 hrs by microscopic method | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 6. | ALA4415109 | F | Induction of cell aggregation in human MEC1 at 20 uM after 2 hrs by microcopic method | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 7. | ALA4415115 | F | Induction of cell death in human MEC1 cells at 5 uM in presence of ryanodine inhibitor dantrolene administered 1 hr post dantrolene treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 8. | ALA4415116 | F | Induction of cell death in human MEC1 cells at 5 uM in presence of PLCgamma1 inhibitor U73122 administered 1 hr post U73122 treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 9. | ALA4415117 | F | Induction of cell death in human MEC1 cells at 5 uM in presence of IP3R inhibitor 2-APB administered 1 hr post 2-APB treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 10. | ALA4415118 | F | Cytotoxicity against human A549 cells assessed as induction of cell death after 6 hrs by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 3 | ALA4414552 | cell-based format | Scientific Literature | |
| 11. | ALA4415124 | F | Induction of cell death in human A549 cells at 10 uM in presence of PLCgamma1 inhibitor U73122 administered 1 hr post U73122 treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 12. | ALA4415125 | F | Induction of cell death in human A549 cells at 10 uM in presence of IP3R inhibitor 2-APB administered 1 hr post 2-APB treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 13. | ALA4415126 | F | Induction of cell death in human A549 cells at 10 uM in presence of ryanodine inhibitor dantrolene administered 1 hr post dantrolene treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 14. | ALA4415127 | F | Induction of cell death in human A549 cells at 50 uM in presence of ryanodine inhibitor dantrolene/PLCgamma1 inhibitor U73122/IP3R inhibitor 2-APB by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 15. | ALA4415129 | F | Induction of cell death in human A549 cells at 10 uM administered 30 mins post Q-VD-OPh treatment in serum-free medium by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 16. | ALA4415130 | F | Induction of cell adhesion in human A549 cells | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 17. | ALA4415131 | F | Induction of cell death in human A549 cells assessed as reduction in cell index measured every minute for 2 hrs by RTCA analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 18. | ALA4415132 | F | Disruption of membrane integrity in human A549 cells assessed as increase in adenylate kinase release at 5 to 40 uM by ToxiLight bioassay | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature | |
| 19. | ALA4415136 | P | Solubility of the compound in water | 1 | ALA4414552 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA4415139 | F | Induction of cell death in human MEC1 cells at 5 uM in presence of caspase inhibitor Q-VD-OPH administered 30 mins post Q-VD-OPH treatment in serum-free medium by Annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4414552 | cell-based format | Scientific Literature |
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