# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406060 | Binding | Displacement of [3H]-SCH23390 from recombinant human D1 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | cell-based format | Scientific Literature | |
2. | ALA4406061 | Binding | Displacement of [3H]-N-methylspiperone from recombinant human D2 receptor stably expressed in fibroblast cell membranes measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | cell-based format | Scientific Literature | |
3. | ALA4406062 | Binding | Displacement of [3H]-N-methylspiperone from recombinant human D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | single protein format | Scientific Literature | |
4. | ALA4406063 | Binding | Displacement of [3H]-N-methylspiperone from recombinant human D4 receptor stably expressed in HEK cell membranes measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | cell-based format | Scientific Literature | |
5. | ALA4406064 | Binding | Displacement of [3H]-SCH23390 from recombinant human D5 receptor transiently expressed in HEKT cell membranes measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | cell-based format | Scientific Literature | |
6. | ALA4406065 | Binding | Displacement of [3H]-Mesulergine from recombinant human 5HT2C receptor expressed in HEKT cell membranes measured after 90 mins by microbeta scintillation counting method | Homo sapiens | 51 | ALA4402598 | cell-based format | Scientific Literature | |
7. | ALA4406071 | Functional | Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation preincubated for 15 mins followed by isoproterenol addition by Glosensor-based luminescence assay | Homo sapiens | 11 | ALA4402598 | cell-based format | Scientific Literature | |
8. | ALA4406072 | Functional | Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation preincubated for 15 mins followed by isoproterenol addition by Glosensor-based luminescence assay relative to dopamine | Homo sapiens | 10 | ALA4402598 | cell-based format | Scientific Literature | |
9. | ALA4406074 | Binding | Agonist activity at D3 receptor (unknown origin) expressed in human HTLA cells assessed as induction of beta-arrestin2 recruitment measured after 16 hrs by Bright-glo reagent based Tango luminescence assay | Homo sapiens | 7 | ALA4402598 | cell-based format | Scientific Literature | |
10. | ALA4406075 | Binding | Agonist activity at D3 receptor (unknown origin) expressed in human HTLA cells assessed as induction of beta-arrestin2 recruitment measured after 16 hrs by Bright-glo reagent based Tango luminescence assay relative to control | Homo sapiens | 7 | ALA4402598 | cell-based format | Scientific Literature | |
11. | ALA4406078 | Functional | Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay | Homo sapiens | 6 | ALA4402598 | cell-based format | Scientific Literature | |
12. | ALA4406079 | Functional | Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay relative to 5-HT | Homo sapiens | 5 | ALA4402598 | cell-based format | Scientific Literature | |
13. | ALA4406080 | ADME | Agonist activity at 5HT2A receptor (unknown origin) expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay | Homo sapiens | 8 | ALA4402598 | cell-based format | Scientific Literature | |
14. | ALA4406081 | ADME | Agonist activity at 5HT2B receptor (unknown origin) expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay | Homo sapiens | 8 | ALA4402598 | cell-based format | Scientific Literature |