# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4427348 | Binding | Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 25 | ALA4425164 | single protein format | Scientific Literature | |
2. | ALA4427349 | Binding | Activation of human recombinant glucokinase using 5 mM glucose as substrate in presence of NAD+ and 4% HSA by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 25 | ALA4425164 | single protein format | Scientific Literature | |
3. | ALA4427350 | Binding | Activation of human recombinant glucokinase assessed as enzyme affinity for glucose using 5 mM glucose as substrate in presence of NAD+ by by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 25 | ALA4425164 | single protein format | Scientific Literature | |
4. | ALA4427351 | Binding | Activation of human recombinant glucokinase assessed as Vmax ratio using 0.16 to 80 mM of glucose as substrate in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assay relative to control | Homo sapiens | 25 | ALA4425164 | single protein format | Scientific Literature | |
5. | ALA4427352 | Physicochemical | Solubility of the compound in PBS at pH 7.4 | 6 | ALA4425164 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4427376 | Binding | Ratio of EC50 for activation of human recombinant glucokinase in presence of 4% HSA to EC50 for activation of human recombinant glucokinase in absence of 4% HSA | Homo sapiens | 5 | ALA4425164 | single protein format | Scientific Literature |