# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4369920 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation proximity assay | Homo sapiens | 32 | ALA4368904 | cell-based format | Scientific Literature | |
2. | ALA4369922 | B | Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation proximity assay | Mus musculus | 23 | ALA4368904 | cell-based format | Scientific Literature | |
3. | ALA4369923 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from human A2A adenosine receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by scintillation proximity assay relative to adenosine 5-N-ethyluronamide | Homo sapiens | 16 | ALA4368904 | cell-based format | Scientific Literature | |
4. | ALA4369924 | B | Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from mouse A2A adenosine receptor expressed in HEK293 cell membranes at 10 uM after 60 mins by scintillation proximity assay relative to adenosine 5-N-ethyluronamide | Mus musculus | 7 | ALA4368904 | cell-based format | Scientific Literature | |
5. | ALA4369927 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from human A3A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation proximity assay | Homo sapiens | 28 | ALA4368904 | cell-based format | Scientific Literature | |
6. | ALA4369928 | B | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide from mouse A3A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation proximity assay | Mus musculus | 22 | ALA4368904 | cell-based format | Scientific Literature | |
7. | ALA4369932 | B | Inhibition of 5HT2B (unknown origin) | Homo sapiens | 15 | ALA4368904 | single protein format | Scientific Literature | |
8. | ALA4369933 | B | Inhibition of 5HT2C (unknown origin) | Homo sapiens | 12 | ALA4368904 | single protein format | Scientific Literature | |
9. | ALA4369934 | B | Inhibition of sigma receptor 2 (unknown origin) | Homo sapiens | 15 | ALA4368904 | single protein format | Scientific Literature | |
10. | ALA4369936 | B | Inhibition of TSPO (unknown origin) | Homo sapiens | 6 | ALA4368904 | single protein format | Scientific Literature | |
11. | ALA4369938 | B | Inhibition of histamine H2 receptor (unknown origin) | Homo sapiens | 2 | ALA4368904 | single protein format | Scientific Literature | |
12. | ALA4369954 | F | Induction of hypothermia in C57BL/6J mouse assessed as body temperature at 10 mg/kg, ip measured at 60 mins post dose (Rvb = 36.3 +/- 0.8 degC) | Mus musculus | 4 | ALA4368904 | organism-based format | Scientific Literature | |
13. | ALA4369957 | F | Induction of hypothermia in C57BL/6J mouse assessed as activity counts at 10 mg/kg, ip measured at 60 mins post dose (Rvb = 15.5 +/- 5.5 No_unit) | Mus musculus | 4 | ALA4368904 | organism-based format | Scientific Literature |