# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4344009 | Binding | Inhibition of wild type human STING by SPA assay | Homo sapiens | 3 | ALA4342439 | single protein format | Scientific Literature | |
2. | ALA5096702 | Binding | Agonist activity to C-terminal domain human STING (139 to 379 residues) | Homo sapiens | 2 | ALA5096152 | single protein format | Scientific Literature | |
3. | ALA5116527 | Binding | Inhibition of human wild type STING | Homo sapiens | 1 | ALA5113434 | single protein format | Scientific Literature | |
4. | ALA5162234 | Functional | Activation of IRF-mediated immune response in human THP1-Dual KO-STING cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 43 | ALA5154810 | cell-based format | Scientific Literature | |
5. | ALA5162235 | Binding | Induction of STING dependent immune response in human wild type THP1-Dual cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 44 | ALA5154810 | cell-based format | Scientific Literature | |
6. | ALA5162239 | Binding | Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 21 | ALA5154810 | cell-based format | Scientific Literature | |
7. | ALA5162240 | Functional | Cytotoxicity against human wild type THP1-Dual cells assessed as residual cell viability by CellTiter96 Aqueous One Solution Cell Proliferation Assay | Homo sapiens | 41 | ALA5154810 | cell-based format | Scientific Literature | |
8. | ALA5162241 | Functional | Cytotoxicity against human THP1-Dual KO-STING cells assessed as residual cell viability by CellTiter96 Aqueous One Solution Cell Proliferation Assay | Homo sapiens | 39 | ALA5154810 | cell-based format | Scientific Literature |