# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4481328 | B | Inhibition of full length His-tagged human DDX3X expressed in Escherichia coli assessed as reduction in DDX3X helicase activity using FAM-labeled double stranded RNA as substrate after 40 mins by FRET assay relative to control | Homo sapiens | 21 | assay format | Scientific Literature | ||
2. | ALA4481334 | A | Cytotoxicity against human HuH7 cells after 3 days by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA4481337 | F | Antiviral activity against West Nile virus infected in human HuH7 cells incubated for 4 days by crystal violet staining based plaque reduction assay | West Nile virus | 10 | organism-based format | Scientific Literature | ||
4. | ALA4481340 | A | Apparent permeability of the compound by PAMPA | 7 | assay format | Scientific Literature | |||
5. | ALA4481341 | P | Aqueous solubility of the compound at 1 mg after 24 to 36 hrs by LC-MS/MS analysis | 7 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4481342 | A | Metabolic stability in human liver microsomes at 50 uM after 60 mins in presence of NADPH-generating system by LC-UV-MS analysis | Homo sapiens | 7 | microsome format | Scientific Literature |