# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354244 | B | Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2347 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate preincubated with enzyme for 30 mins followed by substrate addition by HTRF method | Homo sapiens | 20 | assay format | Scientific Literature | ||
2. | ALA4354245 | B | Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 1620 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate preincubated with enzyme for 30 mins followed by substrate addition by HTRF method | Homo sapiens | 20 | assay format | Scientific Literature | ||
3. | ALA4354246 | B | Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 1620 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate at 1 uM preincubated with enzyme for 30 mins followed by substrate addition by HTRF method relative to control | Homo sapiens | 20 | assay format | Scientific Literature | ||
4. | ALA4354247 | B | Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2347 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate at 1 uM preincubated with enzyme for 30 mins followed by substrate addition by HTRF method relative to control | Homo sapiens | 20 | assay format | Scientific Literature | ||
5. | ALA4354248 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
6. | ALA4354249 | F | Antiproliferative activity against ALK-addicted human NCI-H3122 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
7. | ALA4354250 | F | Antiproliferative activity against ROS1-addicted human HCC78 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
8. | ALA4354251 | B | Inhibition of BTK (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA4354252 | B | Inhibition of CDK2/cyclinA (unknown origin) at 1 uM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
10. | ALA4354253 | B | Inhibition of FER (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA4354254 | B | Inhibition of FES (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA4354255 | B | Inhibition of IGF1R (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA4354256 | B | Inhibition of JAK2 (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA4354257 | B | Inhibition of TNK2 (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA4354258 | B | Inhibition of EGFR (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA4354259 | B | Inhibition of KDR (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA4354260 | B | Inhibition of LTK (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA4354261 | B | Inhibition of MAPK9 (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4354262 | B | Inhibition of MET (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA4354263 | B | Inhibition of NEK2 (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature |