| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4354244 | Binding | Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2347 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate preincubated with enzyme for 30 mins followed by substrate addition by HTRF method | Homo sapiens | 20 | ALA4351011 | assay format | Scientific Literature | |
| 2. | ALA4354245 | Binding | Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 1620 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate preincubated with enzyme for 30 mins followed by substrate addition by HTRF method | Homo sapiens | 20 | ALA4351011 | assay format | Scientific Literature | |
| 3. | ALA4354246 | Binding | Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 1620 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate at 1 uM preincubated with enzyme for 30 mins followed by substrate addition by HTRF method relative to control | Homo sapiens | 20 | ALA4351011 | assay format | Scientific Literature | |
| 4. | ALA4354247 | Binding | Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2347 residues) expressed in baculovirus system assessed as decrease in substrate phosphorylation using TK peptide as substrate at 1 uM preincubated with enzyme for 30 mins followed by substrate addition by HTRF method relative to control | Homo sapiens | 20 | ALA4351011 | assay format | Scientific Literature | |
| 5. | ALA4354248 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | ALA4351011 | cell-based format | Scientific Literature | |
| 6. | ALA4354249 | Functional | Antiproliferative activity against ALK-addicted human NCI-H3122 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | ALA4351011 | cell-based format | Scientific Literature | |
| 7. | ALA4354250 | Functional | Antiproliferative activity against ROS1-addicted human HCC78 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 20 | ALA4351011 | cell-based format | Scientific Literature | |
| 8. | ALA4354251 | Binding | Inhibition of BTK (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 9. | ALA4354252 | Binding | Inhibition of CDK2/cyclinA (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | protein complex format | Scientific Literature | |
| 10. | ALA4354253 | Binding | Inhibition of FER (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 11. | ALA4354254 | Binding | Inhibition of FES (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 12. | ALA4354255 | Binding | Inhibition of IGF1R (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 13. | ALA4354256 | Binding | Inhibition of JAK2 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 14. | ALA4354257 | Binding | Inhibition of TNK2 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 15. | ALA4354258 | Binding | Inhibition of EGFR (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 16. | ALA4354259 | Binding | Inhibition of KDR (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 17. | ALA4354260 | Binding | Inhibition of LTK (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 18. | ALA4354261 | Binding | Inhibition of MAPK9 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 19. | ALA4354262 | Binding | Inhibition of MET (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature | |
| 20. | ALA4354263 | Binding | Inhibition of NEK2 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA4351011 | single protein format | Scientific Literature |
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