# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA648767 | B | Binding affinity for Angiotensin II receptor, type 1 determined using [125I]- labeled [Sar1,Ile8] angiotensin II in rat adrenocortical membranes | 16 | cell membrane format | Scientific Literature | |||
2. | ALA643593 | B | Receptor binding affinity for Angiotensin II receptor, type 2 determined | 1 | single protein format | Scientific Literature | |||
3. | ALA768048 | F | Functional antagonism measured by its ability to block angiotensin II induced contractions in rabbit aortic smooth muscle strips | Oryctolagus cuniculus | 16 | tissue-based format | Scientific Literature | ||
4. | ALA770191 | F | Tested for non competitive antagonist of the vasoconstrictor effects of Angiotensin II | Oryctolagus cuniculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA778353 | F | Oral dose required for sustained reduction in blood pressure extended to 72 hr in salt depleted spontaneously hypertensive rats | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
6. | ALA781300 | F | Effective dose iv, to antagonize the pressor response to exogenous Angiotensin II in conscious rats at a dose of 0.03 umol/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA789192 | F | Tested for maximum percent blood pressure fall in salt depleted spontaneously hyper tensive rat at a dose of 10 umol/kg po at 18-24 hr | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
8. | ALA794660 | F | Tested for maximum percent reduction in mean arterial blood pressure at an oral dose of 30 umol/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA1669993 | F | Antihypertensive activity in iv dosed salt depleted SHR rat model assessed as reduction of angiotensin 2-induced response | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA1669994 | F | Inhibition of angiotensin 2-induced response in iv dosed conscious Sprague-Dawley rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
11. | ALA1669995 | B | Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin AT1 receptor in rat aortic smooth muscle cells | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
12. | ALA1669996 | B | Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin AT1 receptor in rat adrenal cortical membranes | Rattus norvegicus | 2 | cell membrane format | Scientific Literature | ||
13. | ALA1670335 | F | Antihypertensive activity in iv dosed salt depleted SHR rat model assessed as reduction of angiotensin 2-induced mean arterial pressure at 30 uM/mg | Rattus norvegicus | 1 | organism-based format | Scientific Literature |