# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA633673 | A | Plasma half life was determined in pigs | Sus scrofa | 10 | ALA1133591 | organism-based format | Scientific Literature | |
2. | ALA677178 | B | Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells | 36 | ALA1133591 | cell-based format | Scientific Literature | ||
3. | ALA4018830 | F | Agonist activity at human GLP1 receptor expressed in HEK293 cells harboring mCerulean and mCitrine fused Epac protein assessed as increase in cAMP level up to 30 mins by fluorescence assay | Homo sapiens | 9 | ALA4017493 | cell-based format | Scientific Literature | |
4. | ALA4018831 | U | Induction of self aggregation in pH 7.4 PBS buffer assessed as retention volume by size exclusion chromatographic method | 5 | ALA4017493 | assay format | Scientific Literature | ||
5. | ALA4018832 | U | Induction of monodisperse self aggregation in pH 7.4 PBS buffer by dynamic light scattering method | 2 | ALA4017493 | assay format | Scientific Literature | ||
6. | ALA4018833 | U | Induction of self aggregation in pH 7.4 PBS buffer assessed as supramolecular hydrodynamic radii at 1 mg/ml by dynamic light scattering method | 2 | ALA4017493 | assay format | Scientific Literature | ||
7. | ALA4018834 | U | Induction of self aggregation in pH 7.4 PBS buffer assessed as polydispersity index at 1 mg/ml by dynamic light scattering method | 2 | ALA4017493 | assay format | Scientific Literature | ||
8. | ALA4018838 | F | Antidiabetic activity in NMRI mouse assessed as blood glucose AUC (0 to 120 mins) at 10 nmol/ml, sc administered 45 mins prior to glucose challenge by OGTT (Rvb = 1725 +/- 257 mmol/L) | Mus musculus | 3 | ALA4017493 | organism-based format | Scientific Literature | |
9. | ALA4018839 | F | Antiobesity activity in NMRI mouse assessed as food intake at 10 nmol/ml, sc measured after 20 hrs (Rvb = 3.51 +/- 0.49 g) | Mus musculus | 2 | ALA4017493 | organism-based format | Scientific Literature | |
10. | ALA4018846 | A | Half life in sc dosed human | Homo sapiens | 1 | ALA4017493 | organism-based format | Scientific Literature | |
11. | ALA4018847 | A | Tmax in sc dosed human | Homo sapiens | 1 | ALA4017493 | organism-based format | Scientific Literature | |
12. | ALA4018848 | A | Half life in sc dosed mouse | Mus musculus | 1 | ALA4017493 | organism-based format | Scientific Literature | |
13. | ALA4018849 | A | Tmax in sc dosed mouse | Mus musculus | 1 | ALA4017493 | organism-based format | Scientific Literature | |
14. | ALA4052169 | F | Agonist activity at human GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 21 | ALA4049452 | cell-based format | Scientific Literature | |
15. | ALA4052170 | F | Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 21 | ALA4049452 | cell-based format | Scientific Literature | |
16. | ALA4052172 | F | Antiobese activity in diet induced obese C57BL/6N mouse assessed as overall weight change at 50 ug/kg, sc twice daily morning at the begining of the light phase and in the evening prior lights off for 33 days (Rvb = 0.2 +/- 0.7%) | Mus musculus | 2 | ALA4049452 | organism-based format | Scientific Literature | |
17. | ALA4052173 | A | Cmax in C57/BL6 mouse at 1 mg/kg, sc by LC-MS/MS analysis | Mus musculus | 3 | ALA4049452 | organism-based format | Scientific Literature | |
18. | ALA4052174 | A | Tmax in C57/BL6 mouse at 1 mg/kg, sc by LC-MS/MS analysis | Mus musculus | 3 | ALA4049452 | organism-based format | Scientific Literature | |
19. | ALA4052175 | A | AUC in C57/BL6 mouse at 1 mg/kg, sc by LC-MS/MS analysis | Mus musculus | 3 | ALA4049452 | organism-based format | Scientific Literature | |
20. | ALA4052176 | A | Half life in C57/BL6 mouse at 1 mg/kg, sc by LC-MS/MS analysis | Mus musculus | 3 | ALA4049452 | organism-based format | Scientific Literature |