# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346484 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 16 to 20 hrs by microdilution method | Staphylococcus aureus | 85 | organism-based format | Scientific Literature | ||
2. | ALA4346486 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 measured after 16 to 20 hrs in presence of bovine serum albumin by microdilution method | Staphylococcus aureus | 22 | organism-based format | Scientific Literature | ||
3. | ALA4346487 | F | Antibacterial activity against clindamycin/erythromycin/spectinomycin-resistant mec-positive Staphylococcus aureus NRS70 measured after 16 to 20 hrs by microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
4. | ALA4346488 | F | Antibacterial activity against multi-drug resistant mecA-positive Staphylococcus aureus NRS119 measured after 16 to 20 hrs by microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
5. | ALA4346489 | F | Antibacterial activity against multi-drug resistant mecA-positive Staphylococcus aureus ATCC 27660 measured after 16 to 20 hrs by microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
6. | ALA4346490 | F | Antibacterial activity against multi-drug resistant mec-positive Staphylococcus aureus USA300 measured after 16 to 20 hrs by microdilution method | Staphylococcus aureus | 23 | organism-based format | Scientific Literature | ||
7. | ALA4346491 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 16 hrs by XTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
8. | ALA4346492 | F | Selectivity ratio of MIC for Staphylococcus aureus ATCC 29213 in presence of bovine serum albumin to MIC for Staphylococcus aureus ATCC 29213 in absence of bovine serum albumin | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
9. | ALA4346493 | F | Antibacterial activity against Staphylococcus epidermidis ATCC 35547 measured after 16 to 20 hrs by microdilution method | Staphylococcus epidermidis | 2 | organism-based format | Scientific Literature | ||
10. | ALA4346494 | F | Antibacterial activity against Staphylococcus haemolyticus ATCC 29970 measured after 16 to 20 hrs by microdilution method | Staphylococcus haemolyticus | 2 | organism-based format | Scientific Literature | ||
11. | ALA4346495 | F | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 measured after 16 to 20 hrs by microdilution method | Streptococcus pneumoniae | 2 | organism-based format | Scientific Literature | ||
12. | ALA4346496 | F | Antibacterial activity against Clostridium difficile ATCC 43255 measured after 16 to 20 hrs by microdilution method | Clostridioides difficile | 2 | organism-based format | Scientific Literature | ||
13. | ALA4346497 | F | Antibacterial activity against Bacillus cereus ATCC 13061 measured after 16 to 20 hrs by microdilution method | Bacillus cereus | 2 | organism-based format | Scientific Literature | ||
14. | ALA4346498 | F | Antibacterial activity against Bacillus licheniformis ATCC 12759 measured after 16 to 20 hrs by microdilution method | Bacillus licheniformis | 2 | organism-based format | Scientific Literature | ||
15. | ALA4346499 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 measured after 16 to 20 hrs by microdilution method | Enterococcus faecalis | 2 | organism-based format | Scientific Literature | ||
16. | ALA4346500 | T | Selectivity index, ratio of IC50 for human HeLa cells to MIC for clindamycin/erythromycin/spectinomycin-resistant mec-positive Staphylococcus aureus NRS70 | 23 | assay format | Scientific Literature | |||
17. | ALA4346501 | A | Protein binding in human plasma at 10 uM measured after 6 hrs UV-UPLC based rapid equilibrium dialysis method | Homo sapiens | 22 | cell-free format | Scientific Literature | ||
18. | ALA4346503 | A | AUC (0 to last) in ICR mouse at 10 mg/kg, iv by UV-UPLC analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
19. | ALA4346504 | A | AUC (0 to infinity) in ICR mouse at 10 mg/kg, iv by UV-UPLC analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
20. | ALA4346505 | A | Elimination half life in ICR mouse at 10 mg/kg, iv by UV-UPLC analysis | Mus musculus | 2 | organism-based format | Scientific Literature |