# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4325427 | Binding | Inhibition of p300 (unknown origin) using histone H3 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate and [3H]acetyl-CoA addition and measured after 60 mins by scintillation counting analysis | Homo sapiens | 28 | ALA4321876 | single protein format | Scientific Literature | |
2. | ALA4325428 | Functional | Antiproliferative activity against human MV4-11 cells measured after 3 days by celltiter-glo luminescence assay | Homo sapiens | 28 | ALA4321876 | cell-based format | Scientific Literature | |
3. | ALA4325429 | ADME | Intrinsic clearance in human liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Homo sapiens | 28 | ALA4321876 | microsome format | Scientific Literature | |
4. | ALA4325430 | ADME | Intrinsic clearance in rat liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Rattus norvegicus | 28 | ALA4321876 | microsome format | Scientific Literature | |
5. | ALA4325431 | ADME | Intrinsic clearance in mouse liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis | Mus musculus | 28 | ALA4321876 | microsome format | Scientific Literature | |
6. | ALA5033899 | Binding | Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scintillation counting assay | Homo sapiens | 16 | ALA5032535 | single protein format | Scientific Literature | |
7. | ALA5033900 | Binding | Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scintillation counting assay | Homo sapiens | 16 | ALA5032535 | single protein format | Scientific Literature | |
8. | ALA5033901 | Functional | Antiproliferative activity against human OVCAR-3 cells assessed as inhibition of cell proliferation measured after 120 hrs by Cell-titre glo assay | Homo sapiens | 6 | ALA5032535 | cell-based format | Scientific Literature | |
9. | ALA5033902 | Functional | Antiproliferative activity against human A2780 cells assessed as inhibition of cell proliferation measured after 120 hrs by Cell-titre glo assay | Homo sapiens | 6 | ALA5032535 | cell-based format | Scientific Literature | |
10. | ALA5033903 | ADME | Stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 6 | ALA5032535 | microsome format | Scientific Literature | |
11. | ALA5033904 | ADME | Stability in rat liver microsomes assessed as intrinsic clearance | Rattus norvegicus | 6 | ALA5032535 | microsome format | Scientific Literature | |
12. | ALA5033905 | ADME | Stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 6 | ALA5032535 | microsome format | Scientific Literature |