# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374341 | Functional | Antiviral activity against HCV genotype 1b Con1 infected in human HuH5.2 cells assessed as reduction in viral replication incubated for 3 days by luciferase reporter gene assay | Hepacivirus hominis | 11 | ALA4373658 | organism-based format | Scientific Literature | |
2. | ALA4374343 | Functional | Antiviral activity against HCV genotype 4a ED43 infected in human HuH7.5 cells assessed as reduction in viral replication incubated for 3 days by luciferase reporter gene assay | Hepacivirus hominis | 9 | ALA4373658 | organism-based format | Scientific Literature | |
3. | ALA4374345 | ADME | Cytotoxicity against human HuH5.2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 11 | ALA4373658 | cell-based format | Scientific Literature | |
4. | ALA4374346 | Toxicity | Selectivity index, ratio of CC50 for human Huh5.2 cells to EC50 for HCV genotype 1b Con1 | 10 | ALA4373658 | assay format | Scientific Literature | ||
5. | ALA4374348 | Toxicity | Selectivity index, ratio of CC50 for human Huh5.2 cells to EC50 for HCV genotype 4a ED43 | 9 | ALA4373658 | assay format | Scientific Literature | ||
6. | ALA4374352 | Functional | Antitrypanosomal activity against Trypanosoma brucei 221 bloodstream form assessed as inhibition of growth incubated for 4 days by resazurin dye based fluorescence assay | Trypanosoma brucei | 11 | ALA4373658 | organism-based format | Scientific Literature | |
7. | ALA4374353 | Functional | Antitrypanosomal activity against Trypanosoma cruzi strain CL Brener epimastigotes form assessed as inhibition of growth incubated for 4 days by resazurin dye based fluorescence assay | Trypanosoma cruzi | 10 | ALA4373658 | organism-based format | Scientific Literature | |
8. | ALA4374354 | ADME | Cytotoxicity against rat L6 cells assessed as reduction in cell viability incubated for 6 days by resazurin dye based fluorescence assay | Rattus norvegicus | 10 | ALA4373658 | cell-based format | Scientific Literature | |
9. | ALA4374355 | Toxicity | Selectivity index, ratio of CC50 for rat L6 cells to EC50 for Trypanosoma brucei 221 bloodstream form | 9 | ALA4373658 | assay format | Scientific Literature |