# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4385916 | Functional | Antiproliferative activity against Mcl1-sensitive human NCI-H929 cells assessed as cell growth inhibition after 72 hrs by Celltiter-glo luminescence assay | Homo sapiens | 9 | ALA4385603 | cell-based format | Scientific Literature | |
2. | ALA4385919 | Binding | Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs by TR-FRET assay | Homo sapiens | 9 | ALA4385603 | single protein format | Scientific Literature | |
3. | ALA4385920 | Binding | Inhibition of FITC-labeled Bak peptide binding to MBP-fused Mcl-1 (unknown origin) measured after 3 hrs in presence of 1% fetal bovine serum by TR-FRET assay | Homo sapiens | 9 | ALA4385603 | single protein format | Scientific Literature | |
4. | ALA4385921 | Functional | Antiproliferative activity against Mcl1-insensitive human K562 cells assessed as cell growth inhibition after 72 hrs by Celltiter-glo luminescence assay | Homo sapiens | 9 | ALA4385603 | cell-based format | Scientific Literature | |
5. | ALA4385922 | Functional | Induction of apoptosis in Mcl-1 sensitive human NCI-H929 cells assessed as activation of caspase3/7 for 3 hrs by Caspase-Glo luminescence analysis | Homo sapiens | 9 | ALA4385603 | cell-based format | Scientific Literature | |
6. | ALA4385924 | Binding | Inhibition of FITC-labeled Bak peptide binding to Bcl-xL (unknown origin) after 0.5 hrs by fluorescence polarization assay | Homo sapiens | 8 | ALA4385603 | single protein format | Scientific Literature | |
7. | ALA4385925 | Binding | Inhibition of FITC-labeled Bak peptide binding to Bcl-2 (unknown origin) after 0.5 hrs by fluorescence polarization assay | Homo sapiens | 8 | ALA4385603 | single protein format | Scientific Literature |