#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4479482	Functional	Positive allosteric modulation activity at human M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl choline-induced response by calcium mobilization assay	Homo sapiens	35	ALA4477243	cell-based format	Scientific Literature
2.	ALA4479483	Functional	Positive allosteric modulation activity at human M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl choline-induced response by calcium mobilization assay relative to acetylcholine	Homo sapiens	17	ALA4477243	cell-based format	Scientific Literature
3.	ALA4479484	Functional	Positive allosteric modulation activity at rat M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl choline-induced response by calcium mobilization assay	Rattus norvegicus	35	ALA4477243	cell-based format	Scientific Literature
4.	ALA4479485	Functional	Positive allosteric modulation activity at rat M4 receptor expressed in CHO cells co-expressing Gqi5 protein assessed as potentiation of EC20 acetyl choline-induced response by calcium mobilization assay relative to acetylcholine	Rattus norvegicus	17	ALA4477243	cell-based format	Scientific Literature
5.	ALA4479486	ADME	Inhibition of Cytochrome P450 (unknown origin)	Homo sapiens	16	ALA4477243	protein format	Scientific Literature
6.	ALA4479487	ADME	Inhibition of CYP1A2 (unknown origin)	Homo sapiens	16	ALA4477243	single protein format	Scientific Literature
7.	ALA4479491	ADME	Fraction unbound in human plasma	Homo sapiens	17	ALA4477243	cell-free format	Scientific Literature
8.	ALA4479492	ADME	Fraction unbound in rat plasma	Rattus norvegicus	17	ALA4477243	cell-free format	Scientific Literature
9.	ALA4479497	ADME	Ratio of drug level in Sprague-Dawley rat brain to plasma at 0.2 to 0.25 mg/kg, iv administered as cassette dose measured 0.25 hrs post dose	Rattus norvegicus	18	ALA4477243	organism-based format	Scientific Literature
10.	ALA4479498	ADME	Unbound brain to plasma concentration ratio in Sprague-Dawley rat at 0.2 to 0.25 mg/kg, iv administered as cassette dose measured 0.25 hrs post dose	Rattus norvegicus	16	ALA4477243	organism-based format	Scientific Literature