# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4344613 | B | Inhibition of Granzyme A (unknown origin) expressed in Pichia pastoris assessed as second- order inhibition rate constant (Kobs/I ratio) pre-incubated with SK15 substrate for 15 mins before enzyme addition by spectrofluorometry | Homo sapiens | 2 | assay format | Scientific Literature | ||
2. | ALA4344614 | B | Inhibition of Granzyme A (unknown origin) expressed in Pichia pastoris using SK15 substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
3. | ALA4344615 | B | Inhibition of Granzyme B (unknown origin) expressed in Pichia pastoris using GrBref substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA4344616 | B | Inhibition of Granzyme M (unknown origin) expressed in Pichia pastoris using Ac-Lys-Val-Pro-Leu-ACC substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
5. | ALA4344617 | B | Inhibition of PR3 (unknown origin) expressed in Pichia pastoris using Ac-Glu(O-Bzl)-Lys(Ac)-Hyp(Bzl)-Nva-ACC substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
6. | ALA4344618 | B | Inhibition of human neutrophil elastase expressed in Pichia pastoris using Ac-Arg(NO)2-Glu(Bzl)-Oic-Abu-ACC substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA4344619 | B | Inhibition of Granzyme K (unknown origin) expressed in Pichia pastoris using GrKref substrate by spectrofluorometry relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
8. | ALA4344629 | T | Toxicity in human MDA-MB-231 cells assessed as reduction in cell viability at 10 uM incubated for 24 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature |