# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4398328 | F | Antiviral activity against DENV2 Martinique infected in African green monkey Vero E6 cells after 3 to 4 days by RT-PCR analysis | dengue virus type 2 | 1 | ALA4396891 | organism-based format | Scientific Literature | |
2. | ALA4398329 | B | Inhibition of N-terminal His6-tagged DENV3 NS5 RNA dependent RNA polymerase (272 to 900 residues) after 1 hr by fluorescence assay | dengue virus type 3 | 1 | ALA4396891 | single protein format | Scientific Literature | |
3. | ALA4398330 | F | Antiviral activity against DENV4 Dakar infected in African green monkey Vero E6 cells after 3 to 4 days by RT-PCR analysis | dengue virus type 4 | 1 | ALA4396891 | organism-based format | Scientific Literature | |
4. | ALA4398331 | F | Antiviral activity against DENV3 Bolivia infected in African green monkey Vero E6 cells after 3 to 4 days by RT-PCR analysis | dengue virus type 3 | 1 | ALA4396891 | organism-based format | Scientific Literature | |
5. | ALA4398332 | F | Antiviral activity against DENV1 Djibouti infected in African green monkey Vero E6 cells after 3 to 4 days by RT-PCR analysis | dengue virus type 1 | 1 | ALA4396891 | organism-based format | Scientific Literature | |
6. | ALA4615842 | B | Inhibition of Dengue virus NS5 RNA-dependent RNA polymerase assessed as reduction in de novo initiation activity at 30 uM incubated for 1 hr relative to control | dengue virus type 2 | 11 | ALA4613293 | assay format | Scientific Literature | |
7. | ALA4615843 | B | Inhibition of Dengue virus NS5 RNA-dependent RNA polymerase assessed as reduction in elongation activity at 30 uM incubated for 1 hr relative to control | dengue virus type 2 | 11 | ALA4613293 | assay format | Scientific Literature | |
8. | ALA4615844 | B | Inhibition of Dengue virus NS5 RNA-dependent RNA polymerase assessed as reduction in elongation activity incubated for 1 hr | dengue virus type 2 | 11 | ALA4613293 | assay format | Scientific Literature | |
9. | ALA4615845 | A | Cytotoxicity against human HuH7 cells assessed as reduction in cell viability incubated for 48 hrs by CellTiter Glo Luminescent assay | Homo sapiens | 12 | ALA4613293 | cell-based format | Scientific Literature | |
10. | ALA4615846 | F | Antiviral activity against Dengue virus 2 EDEN 3295 infected in human HuH7 cells assessed as reduction in virus replication incubated for 48 hrs by plaque reduction assay | dengue virus type 2 | 12 | ALA4613293 | organism-based format | Scientific Literature | |
11. | ALA4615847 | T | Selectivity index, ratio of CC50 for human HuH7 cells to EC50 for Dengue virus 2 EDEN 3295 infected in human HuH7 cells | 7 | ALA4613293 | cell-based format | Scientific Literature | ||
12. | ALA4615848 | F | Antiviral activity against Zika virus H/PF/2013 infected in human HuH7 cells assessed as reduction in virus replication incubated for 24 hrs by plaque reduction assay | Zika virus | 12 | ALA4613293 | organism-based format | Scientific Literature | |
13. | ALA4615849 | T | Selectivity index, ratio of CC50 for human HuH7 cells to EC50 for Zika virus H/PF/2013 infected in human HuH7 cells | 7 | ALA4613293 | cell-based format | Scientific Literature | ||
14. | ALA4615850 | F | Antiviral activity against Dengue virus 1 infected in human HuH7 cells assessed as reduction in virus replication incubated for 48 hrs by plaque reduction assay | dengue virus type 1 | 3 | ALA4613293 | organism-based format | Scientific Literature | |
15. | ALA4615851 | F | Antiviral activity against Dengue virus 3 infected in human HuH7 cells assessed as reduction in virus replication incubated for 48 hrs by plaque reduction assay | dengue virus type 3 | 3 | ALA4613293 | organism-based format | Scientific Literature | |
16. | ALA4615852 | F | Antiviral activity against Dengue virus 4 infected in human HuH7 cells assessed as reduction in virus replication incubated for 48 hrs by plaque reduction assay | dengue virus type 4 | 3 | ALA4613293 | organism-based format | Scientific Literature | |
17. | ALA4615853 | B | Inhibition of Dengue virus full length NS2b-NS3/NS5 interaction incubated for 1 hr by ELISA | Dengue virus | 4 | ALA4613293 | assay format | Scientific Literature | |
18. | ALA5151793 | B | Inhibition of DENV-2 DENV2 NS2B-NS3 | dengue virus type 2 | 1 | ALA5150000 | single protein format | Scientific Literature | |
19. | ALA5225963 | B | Inhibition of SARS-CoV-2 RdRp incubated for 60 mins by fluorescence based assay | Severe acute respiratory syndrome coronavirus 2 | 1 | ALA5223176 | single protein format | Scientific Literature | |
20. | ALA5225964 | F | Antiviral activity against SARS-CoV-2 human/Czech Republic/951/2020 infected in African green monkey Vero cells pretreated with cells followed by viral infection and measured after 48 hrs by viral titer reduction assay | Severe acute respiratory syndrome coronavirus 2 | 1 | ALA5223176 | organism-based format | Scientific Literature |