| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4388514 | Functional | Antiproliferative activity against human NCI-H1299 cells after 72 hrs by cell titer glo assay | Homo sapiens | 15 | ALA4387719 | cell-based format | Scientific Literature | |
| 2. | ALA4388515 | Binding | Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system measured after 1 hr by TR-FRET assay | Homo sapiens | 15 | ALA4387719 | assay format | Scientific Literature | |
| 3. | ALA4388516 | Binding | Inhibition of WEE1 in human NCI-H1299 cells assessed as reduction in Cdc2 phosphorylation at Tyr15 residue measured after 6 hrs by ELISA | Homo sapiens | 15 | ALA4387719 | cell-based format | Scientific Literature | |
| 4. | ALA4388517 | ADME | Clearance in mouse microsomes | Mus musculus | 13 | ALA4387719 | microsome format | Scientific Literature |
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