# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321002 | B | Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting method | Rattus norvegicus | 32 | cell membrane format | Scientific Literature | ||
2. | ALA4321003 | B | Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced calcium ion influx by fluorescence based assay | Mus musculus | 32 | cell-based format | Scientific Literature | ||
3. | ALA4321004 | A | Total clearance in Sprague-Dawley rat at 0.5 mg/kg, iv dosed via cassette dosing | Rattus norvegicus | 32 | organism-based format | Scientific Literature | ||
4. | ALA4321005 | A | Oral bioavailability in Sprague-Dawley rat at 1 mg/kg dosed via cassette dosing | Rattus norvegicus | 32 | organism-based format | Scientific Literature | ||
5. | ALA4321006 | A | Permeability coefficient, ratio of total drug level in brain to plasma in Sprague-Dawley rat at 0.5 mg/kg, iv dosed via cassette dosing measured after 0.5 hrs | Rattus norvegicus | 32 | organism-based format | Scientific Literature |