# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4325161 | Functional | Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay | Homo sapiens | 7 | ALA4321870 | cell-based format | Scientific Literature | |
2. | ALA4325162 | Functional | Inhibition of colony formation in human PANC1 cells incubated for 14 days by crystal violet staining based assay | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
3. | ALA4325163 | Functional | Induction of apoptosis in human PANC1 cells assessed as increase in cleaved caspase-3 level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
4. | ALA4325164 | Functional | Induction of apoptosis in human PANC1 cells assessed as increase in cleaved PARP level incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
5. | ALA4325165 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of MEK at S217/221 at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
6. | ALA4325167 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of ERK(T202/Y204) at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature | |
7. | ALA4325168 | Binding | Inhibition of MEK1/2 in human PANC1 cells assessed as decrease in phosphorylated levels of ERK(T202/Y204) in nuclear fraction at 5 uM incubated for 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4321870 | cell-based format | Scientific Literature |