# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346447 | Binding | Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assay | Homo sapiens | 14 | ALA4342524 | single protein format | Scientific Literature | |
2. | ALA4346448 | Functional | Growth inhibition of human MV4-11 cells after 7 days by WST-8 assay | Homo sapiens | 15 | ALA4342524 | cell-based format | Scientific Literature | |
3. | ALA4346449 | Functional | Growth inhibition of human MOLM13 cells after 7 days by WST-8 assay | Homo sapiens | 15 | ALA4342524 | cell-based format | Scientific Literature | |
4. | ALA4346450 | Functional | Growth inhibition of human HL60 cells after 7 days by WST-8 assay | Homo sapiens | 15 | ALA4342524 | cell-based format | Scientific Literature | |
5. | ALA4346452 | Binding | Covalent binding affinity to human menin assessed as protein-compound complex formation at protein to compound ratio of 1:1.2 after 1 hr by LC-MS analysis relative to control | Homo sapiens | 11 | ALA4342524 | single protein format | Scientific Literature | |
6. | ALA4346453 | Binding | Covalent binding affinity to human menin assessed as protein-compound complex formation at protein to compound ratio of 1:1.2 measured after overnight incubation by LC-MS analysis relative to control | Homo sapiens | 11 | ALA4342524 | single protein format | Scientific Literature |