# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4316276 | B | Inhibition of tubulin polymerization (unknown origin) incubated for 15 mins followed by GTP addition and measured for 20 mins by spectrophotometry | Homo sapiens | 70 | ALA4312029 | protein complex format | Scientific Literature | |
2. | ALA4316277 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 96 hrs by MTT assay | Homo sapiens | 70 | ALA4312029 | cell-based format | Scientific Literature | |
3. | ALA5253945 | F | Effect on total cofilin protein level in human LAMA-84 cells at 100 nM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
4. | ALA5253946 | F | Effect on total beta-catenin protein level in human LAMA-84 cells at 100 nM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
5. | ALA5253947 | B | Inhibition of BCR-ABL phospho-activation in human LAMA-84 cells at 100 nM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
6. | ALA5253948 | F | Induction of apoptosis in human KU812 cells assessed as increase in PARP cleavage measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
7. | ALA5253949 | F | Induction of apoptosis in human KU812 cells assessed as upregulation of caspase-3 activation by Western blot analysis | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
8. | ALA5253950 | F | Induction of cell cycle arrest in human KU812 cells assessed as accumulation of cells at sub-G1 phase incubated for 2 to 8 hrs by RNase/PI staining based flow cytometry analysis relative to control | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
9. | ALA5253951 | F | Antiproliferative activity against human LAMA-84 cells expressing BCR/ABL assessed as cell growth inhibition at 12 nM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
10. | ALA5253952 | F | Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 3 days by trypan blue exclusion assay | Homo sapiens | 16 | ALA5252540 | cell-based format | Scientific Literature | |
11. | ALA5253953 | B | Inhibition of tubulin (unknown origin) polymerization preincubated for 15 mins followed by GTP addition by turbidity based spectrophotometer analysis | Homo sapiens | 16 | ALA5252540 | protein complex format | Scientific Literature | |
12. | ALA5253954 | B | Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 5 uM incubated for 10 mins relative to control | Homo sapiens | 15 | ALA5252540 | protein complex format | Scientific Literature | |
13. | ALA5253957 | F | Cytotoxicity against human KYSE-150 cells assessed as cell growth inhibition incubated for 48 to 96 hrs by celltiter-flor reagent based fluorescence assay | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
14. | ALA5253958 | F | Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
15. | ALA5253959 | F | Cytotoxicity against human HepG2 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
16. | ALA5253960 | F | Antiproliferative activity against human KU812 cells expressing BCR/ABL assessed as cell growth inhibition at 12 nM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
17. | ALA5253961 | T | Cytotoxicity against human PBMC cells assessed as reduction in cell viability up to 1 uM incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
18. | ALA5253962 | F | Cytotoxicity against imatinib mesylate sensitive human KBM5 cells expressing wild type BCR/ABL assessed as cell growth inhibition | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
19. | ALA5253963 | F | Cytotoxicity against imatinib mesylate resistant human KBM5 cells expressing BCR/ABL T315I mutant assessed as cell growth inhibition | Homo sapiens | 1 | ALA5252540 | cell-based format | Scientific Literature | |
20. | ALA5253964 | F | Induction of mitochondrial transmembrane potential loss in human KU812 cells assessed as increase in green fluorescence signal at 100 nM incubated for 8 hrs by fluorescent cationic dye based microscopic analysis (Rvb = 2.2%) | Homo sapiens | 2 | ALA5252540 | cell-based format | Scientific Literature |