# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4396634 | ADME | Cytotoxicity against mouse L929 cells assessed as cell growth inhibition at 50 ug/ml measured after 72 hrs by MTT method relative to control | Mus musculus | 6 | ALA4393730 | cell-based format | Scientific Literature | |
2. | ALA4396635 | Functional | Antibacterial activity against wild type Staphylococcus aureus 1199 devoid of norA efflux pump assessed as norfloxacin MIC measured after 24 hrs by broth microdilution method (Rvb = 64 +/- 1 microg/ml) | Staphylococcus aureus | 6 | ALA4393730 | organism-based format | Scientific Literature | |
3. | ALA4396636 | Binding | Inhibition of NorA efflux pump in multidrug resistant Staphylococcus aureus 1199B mutant assessed as norfloxacin MIC measured after 24 hrs by broth microdilution method (Rvb = 256 +/- 1 microg/ml) | Staphylococcus aureus | 6 | ALA4393730 | single protein format | Scientific Literature | |
4. | ALA4396637 | Functional | Antibacterial activity against wild type Staphylococcus aureus 1199 devoid of NorA efflux pump measured after 24 hrs by broth microdilution method | Staphylococcus aureus | 6 | ALA4393730 | organism-based format | Scientific Literature | |
5. | ALA4396638 | Functional | Antibacterial activity against multidrug resistant Staphylococcus aureus 1199B mutant strain carrying NorA efflux pump assessed as growth inhibition measured after 24 hrs by broth microdilution method | Staphylococcus aureus | 6 | ALA4393730 | organism-based format | Scientific Literature |