# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4427549 | Binding | Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 27 | ALA4425170 | single protein format | Scientific Literature | |
2. | ALA4427550 | Binding | Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ and glucose 6-phosphate 4% human serum albumin by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 20 | ALA4425170 | single protein format | Scientific Literature | |
3. | ALA4427551 | Binding | Activation of human recombinant glucokinase assessed as substrate affinity monitored over 5 mins in presence of varying concentration of glucose and NAD+ by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 25 | ALA4425170 | single protein format | Scientific Literature | |
4. | ALA4427552 | Binding | Activation of human recombinant glucokinase assessed as substrate Vmax ratio monitored over 5 mins in presence of varying concentration of glucose and NAD+ by glucose 6-phosphate dehydrogenase coupled assay | Homo sapiens | 26 | ALA4425170 | single protein format | Scientific Literature | |
5. | ALA4427553 | ADME | Clearance in rat liver microsomes | Rattus norvegicus | 12 | ALA4425170 | microsome format | Scientific Literature | |
6. | ALA4427586 | Binding | Ratio of EC50 for activation of human recombinant glucokinase in presence of 4% human serum albumin to EC50 for activation of human recombinant glucokinase in absence of 4% human serum | Homo sapiens | 3 | ALA4425170 | single protein format | Scientific Literature |