# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4360836 | Functional | Potency index, ratio of ibrutinib IC50 to compound IC50 for antiproliferative activity against human Raji cells | Homo sapiens | 1 | ALA4359830 | cell-based format | Scientific Literature | |
2. | ALA4360838 | Binding | Inhibition of human recombinant full length N-terminal His tagged BTK expressed in baculovirus infected Sf9 cells at 10 uM using poly (Glu,Tyr) 4:1 as substrate measured after 60 mins in presence of ATP by ADP-Glo kinase assay relative to control | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature | |
3. | ALA4360839 | Binding | Inhibition of human recombinant full length N-terminal His tagged BTK expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate measured after 60 mins in presence of ATP by ADP-Glo kinase assay | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature | |
4. | ALA4360840 | Functional | Antiproliferative activity against human Ramos cells at 40 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature | |
5. | ALA4360841 | Functional | Antiproliferative activity against human Ramos cells measured after 72 hrs by CCK-8 assay | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature | |
6. | ALA4360842 | Functional | Antiproliferative activity against human Raji cells at 40 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature | |
7. | ALA4360843 | Functional | Antiproliferative activity against human Raji cells measured after 72 hrs by CCK-8 assay | Homo sapiens | 51 | ALA4359830 | cell-based format | Scientific Literature |