# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4410741 | Functional | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of C48/80-induced mast cell degranulation preincubated with compound for 30 mins and then treated with C48/80 for 1 hr by neutral red dye based method | Rattus norvegicus | 18 | ALA4406904 | cell-based format | Scientific Literature | |
2. | ALA4410742 | Functional | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of C48/80-induced histamine release preincubated with compound for 30 mins followed by C48/80 stimulation for 1 hr | Rattus norvegicus | 18 | ALA4406904 | cell-based format | Scientific Literature | |
3. | ALA4410743 | Functional | Antiallergic activity in IgE/Ag-stimulated rat RBL2H3 cells assessed as inhibition of HSA-induced beta-hexosaminidase release preincubated with compound for 30 mins and then stimulated with HSA for 15 mins followed by incubation with P-nitrophenyl-N-acetyl-beta-D-glucosaminide for 2 hrs | Rattus norvegicus | 18 | ALA4406904 | cell-based format | Scientific Literature | |
4. | ALA4410751 | Physicochemical | Lipid/water partition co-efficient, log P of the compound | 16 | ALA4406904 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4410752 | Physicochemical | Dissociation constant, pKa of the compound | 16 | ALA4406904 | small-molecule physicochemical format | Scientific Literature |