# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372113 | B | Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method | Rattus norvegicus | 21 | single protein format | Scientific Literature | ||
2. | ALA4372114 | B | Inhibition of histone activated chicken PDE6 using [3H]cGMP as substrate measured after 10 mins by scintillation counting method | Gallus gallus | 21 | assay format | Scientific Literature | ||
3. | ALA4372115 | B | Selectivity index, ratio of IC50 for histone activated chicken PDE6 to IC50 for rat lung PDE5 | 7 | assay format | Scientific Literature | |||
4. | ALA4372116 | A | Cytotoxicity against human A549 cells after 72 hrs by MTT assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
5. | ALA4372117 | U | Selectivity index, ratio of IC50 for human A549 cells to IC50 for rat lung PDE5 | 7 | assay format | Scientific Literature | |||
6. | ALA4372118 | F | Vasorelaxant activity in Wistar rat endothelium intact pulmonary artery rings assessed as inhibition of phenylephrine-induced contraction | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
7. | ALA4372119 | P | Equilibrium solubility of the compound in pH 7.4 phosphate buffer saline at 1 mg sonicated for 1 hr followed by 6 hrs incubation by shake flask method | 7 | small-molecule physicochemical format | Scientific Literature |