| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4313932 | A | Cytotoxicity against rat RAW264.7 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by resazurin staining based assay | Rattus norvegicus | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA4313934 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 promastigotes assessed as reduction in cell viability at 10 uM incubated for 48 hrs by resazurin staining based assay | Leishmania braziliensis | 19 | organism-based format | Scientific Literature | ||
| 3. | ALA4313935 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 10 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 26 | organism-based format | Scientific Literature | ||
| 4. | ALA4313936 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 80 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4313937 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 40 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA4313938 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 30 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA4313939 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 20 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA4313940 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 5 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA4313941 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as cell viability at 2.5 uM incubated for 48 hrs by resazurin staining based assay (Rvb = 10.71 %) | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA4313943 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 promastigotes assessed as reduction in cell viability incubated for 48 hrs by resazurin staining based assay | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA4313944 | A | Cytotoxicity against rat RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by resazurin staining based assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4313945 | F | Antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as reduction in cell viability incubated for 48 hrs by resazurin staining based assay | Leishmania braziliensis | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4313946 | T | Selectivity index, ratio of IC50 of cytotoxicity against rat RAW264.7 cells to IC50 of antileishmanial activity against Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells | 1 | cell-based format | Scientific Literature | |||
| 14. | ALA4313947 | F | Cell cycle arrest in Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells assessed as lobulated cell bodies incubated for 48 hrs by transmission electron microscopy | Leishmania braziliensis | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4313948 | F | Induction of autophagy in Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells incubated for 48 hrs by transmission electron microscopy | Leishmania braziliensis | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4313949 | F | Induction of apoptosis in Leishmania braziliensis MHOM/BR/75/M2904 amastigotes infected in rat RAW264.7 cells incubated for 48 hrs by transmission electron microscopy | Leishmania braziliensis | 1 | organism-based format | Scientific Literature |
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