#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4380723	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 10 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
2.	ALA4380725	Binding	Binding affinity to human wild-type partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by kinomescan assay	Homo sapiens	5	ALA4376874	assay format	Scientific Literature
3.	ALA4380726	Binding	Binding affinity to human wild-type partial length EGFR L858R mutant (R669 to V1011 residues) expressed in bacterial expression system by kinomescan assay	Hofmanni bacterium	5	ALA4376874	assay format	Scientific Literature
4.	ALA4380727	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
5.	ALA4380729	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
6.	ALA4380731	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
7.	ALA4380733	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
8.	ALA4380735	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
9.	ALA4380737	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
10.	ALA4380745	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
11.	ALA4380746	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
12.	ALA4380747	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
13.	ALA4380748	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
14.	ALA4380753	ADME	Effect on AKT level in human HCC827 cells up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
15.	ALA4380754	ADME	Effect on AKT level in human H3255 cells up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
16.	ALA4380759	ADME	Induction of wild-type EGFR degradation in human OVCAR8 cells at up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
17.	ALA4380760	ADME	Induction of wild-type EGFR degradation in human H1299 cells at up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
18.	ALA4380767	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in AKT phosphorylation at 100 nM treated 8 hrs post serum starvation measured after 4 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
19.	ALA4380768	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation measured after 4 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
20.	ALA4380769	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation measured after 12 to 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature