# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4395365 | Functional | Antitrypanosomal activity against bloodstream form of Trypanosoma brucei gambiense Feo reduction in parasite growth after 72 hrs by resazurin dye based fluorescence assay | Trypanosoma brucei gambiense | 93 | ALA4393692 | organism-based format | Scientific Literature | |
2. | ALA4395366 | ADME | Cytotoxicity against human AB943 cells assessed as reduction in cell viability after 5 days resazurin dye based fluorescence assay | Homo sapiens | 26 | ALA4393692 | cell-based format | Scientific Literature | |
3. | ALA4395367 | Toxicity | Selectivity index, ratio of IC50 for human AB943 cells to IC50 of bloodstream form of Trypanosoma brucei gambiense Feo | 26 | ALA4393692 | assay format | Scientific Literature | ||
4. | ALA4395368 | Toxicity | Acute toxicity in ip dosed mouse by Litchfield-Wilcoxon method | Mus musculus | 8 | ALA4393692 | organism-based format | Scientific Literature |