| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4344955 | Binding | Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as substrate preincubated for 30 mins followed by substrate addition and measured for 30 mins by fluorescence based assay | Homo sapiens | 17 | ALA4342480 | assay format | Scientific Literature | |
| 2. | ALA4344956 | Binding | Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarine as substrate preincubated for 30 mins followed by substrate addition and measured for 30 mins by fluorescence based assay | Homo sapiens | 17 | ALA4342480 | assay format | Scientific Literature | |
| 3. | ALA4344957 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 17-HDHA level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 4. | ALA4344958 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 15-HETE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 5. | ALA4344959 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 15-HEPE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 6. | ALA4344960 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 14-HDHA level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 7. | ALA4344961 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 12-HETE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 8. | ALA4344962 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 12-HEPE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 9. | ALA4344963 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 7-HDHA level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 10. | ALA4344964 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 4-HDHA level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 11. | ALA4344965 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 18-HEPE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 12. | ALA4344966 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 5.15-dlHETE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 13. | ALA4344967 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in PGE2 level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 14. | ALA4344968 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in PGD2 level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 15. | ALA4344969 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in PGF2alpha level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 16. | ALA4344970 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in TXBa level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 17. | ALA4344971 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 5-HETE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 18. | ALA4344972 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in 5-HEPE level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 19. | ALA4344973 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in total LTB4 level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature | |
| 20. | ALA4344974 | Functional | Antiinflammatory activity in Escherichia coli O6:K2:H1-induced human M1 macrophage assessed as change in LTB4 level at 1 uM preincubated for 10 mins followed by Escherichia coli O6:K2:H1-stimulation and measured after 180 mins by UPLC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4342480 | cell-based format | Scientific Literature |
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